3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2663 | GTS-21 dihydrochloride | GTS 21 dihydrochloride,DMXB-A,DMBX-anabaseine | 5-HT Receptor , AChR |
GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh. | |||
T19933 | GTS-21 | DMXB-A,GTS21,GTS 21 | AChR |
GTS-21 (DMXB-A) is an α7 nAChR agonist. GTS-21 suppresses inflammation associated with rheumatoid arthritis by inhibiting RA Th1 cell differentiation. | |||
T37390 | NS 6740 | ||
High affinity α7 nAChR partial agonist (Ki = 1.1 nM in rat; Emax < 10% of the response to ACh in rat and human). Inhibits ACh (IC50 = 2.7 nM) at α7 nAChR. Reduces LPS-induced TNF-α release from microglia enriched cultu... |